Renal threshold of Glucose

The renal threshold refers to the concentration of a substance in the blood that, when exceeded, results in the kidneys beginning to excrete that substance into the urine. In the context of blood sugar (glucose) levels, the renal threshold is the blood glucose concentration at which the kidneys start to eliminate excess glucose into the urine.

Normally, the kidneys reabsorb all the glucose filtered by the glomeruli (tiny blood vessels in the kidneys). However, when blood glucose levels rise above a certain threshold, the renal tubules become saturated, and the excess glucose is excreted in the urine. The renal threshold for glucose is typically around 180 mg/dL (milligrams per deciliter).

In individuals with diabetes, the renal threshold can be lower than normal, leading to increased glucose excretion in the urine even at blood glucose levels below the usual threshold. This phenomenon is known as renal glycosuria.

It's important for individuals with diabetes to manage their blood sugar levels within a target range to prevent complications. If blood glucose levels consistently exceed the renal threshold, it may result in increased glucose excretion in the urine, which can contribute to dehydration and may be a sign that diabetes is not well-controlled.


Tm- Transport maximum



Comments

Post a Comment

Popular posts from this blog

GTT-Glucose Tolerance Test

Image
GTT stands for "Glucose Tolerance Test," which is a diagnostic test used to evaluate how the body regulates glucose (sugar) after consuming a specific amount of glucose. The test is often used to diagnose diabetes and gestational diabetes (a type of diabetes that occurs during pregnancy). Here's an overview of how the Glucose Tolerance Test is typically conducted: Fasting: The test often begins in the morning after an overnight fast (usually 8-12 hours of no food or drink other than water). Baseline Blood Sample: A blood sample is taken to measure the fasting blood glucose level. This provides a baseline for comparison. Glucose Drink: The person then drinks a solution containing a specific amount of glucose (usually 75 grams for adults). Blood Samples at Intervals: Blood samples are taken at intervals, typically at 1 hour and 2 hours after drinking the glucose solution. Analysis: Each blood sample is analyzed to measure the level of glucose in the bloodstream. The results...
Read more

Atherosclerosis

Image
Atherosclerosis is a condition where arteries become narrowed and hardened due to the buildup of plaque, composed of fat, cholesterol, and other substances. It can restrict blood flow, leading to various cardiovascular problems. Lifestyle changes and medications are often recommended to manage it. Clinical manifestations of atherosclerosis depend on the arteries affected. Common symptoms include chest pain (angina), shortness of breath, and fatigue. In advanced stages, it can lead to heart attacks, strokes, or peripheral artery disease, causing symptoms like leg pain. Regular check-ups and managing risk factors are crucial for early detection and prevention. Certainly. Atherosclerosis develops over time, often without symptoms until it significantly narrows or blocks arteries. Common clinical manifestations include: 1. **Angina:** Chest pain or discomfort due to reduced blood flow to the heart muscle. 2. **Shortness of Breath:** Especially during physical activity, as the h...
Read more